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Centres of Excellence -> Physical Medicine & Rehabilitation -> Exosomes treatment of postoperative scars

Exosomes treatment of postoperative scars

What are exosomes? 

Exosomes are the latest innovation in regenerative skin medicine, used as an addition to skin rejuvenation treatments and for post-operative scar treatment in combination with microneedling (SkinPen and Dermapen). Exosomes are nanovesicular molecules secreted by stem cells that participate in intercellular communication. This patented technology isolates and purifies exosomes derived from Damascus rose stem cells. They represent a highly concentrated and 99.9% pure form of exosomes and contain growth factors, peptides, glutathione, amino acids, coenzymes, vitamins, and minerals.

Who are the candidates? 

Exosomes and SkinPen/Dermapen are excellent methods for treating scars, including:

  • scars after a cesarean section in women
  • all post-surgical scars (after orthopedic, trauma, abdominal, and other surgeries)
  • skin and tissue damage after radiation therapy, reducing pain, soothing the skin and tissue, and significantly shortening rehabilitation time
  • other skin conditions such as stretch marks, excess skin after pregnancy, or cases of diastasis post-pregnancy, where, in addition to physical therapy and muscle strengthening, the skin is also tightened
  • hypertrophic scars from older surgeries

It is important to note that keloids (the most severe type of scars caused by uncontrolled production of abnormal connective tissue that does not degrade) are not treated with exosomes.

How to achieve optimal results? 

The optimal results can be achieved by combining the following methods:

  • SkinPen/Dermapen (Microneedling):
    Microneedling creates tiny channels in the skin, stimulating the natural skin healing process. It promotes collagen and elastin production, which helps smooth and soften scar texture, improves the appearance of scars, and over time can reduce scar thickness and improve its tone and color.
  • Exosomes:
    Exosomes stimulate regeneration by containing proteins and genetic material that enhance intercellular communication and tissue regeneration. They help reduce redness and inflammation, which is beneficial for post-surgical recovery. Additionally, they promote faster and more effective tissue healing, making scars less visible.

The combination of these treatments can improve the effectiveness of post-surgical scar treatment. It is essential to consult a doctor before undergoing these procedures to ensure they are suitable for your specific condition and skin type.

When to start treating a scar after surgery? 

Scar treatment can begin once the wound has completely healed.

Below are some recommendations on when and how to start treatment:

  • Natural healing process:
    The primary rule is to allow enough time for the wound to heal completely. Depending on the type of surgery, this process can take several weeks to months.
  • Healing symptoms:

It is necessary to wait until all symptoms, such as stretching pain, swelling, dryness, or scabs, have disappeared.

  • Consultation with a doctor:
    It is always recommended to consult a doctor about the optimal time to start treatment, as they can assess the wound’s condition and determine when it is safe to begin.
  • Type of treatment:
    Different types of treatments (e.g., gels, massage, laser, microneedling) have different recommended start times. Some treatments can begin 6–8 weeks after surgery, while others, such as microneedling or laser therapy, are suitable only after a few months.

In any case, an individualized approach is crucial. Every person and every scar is different, so the recommended timeframe will vary depending on specific circumstances.

Exosomes and skin treatment after radiation therapy 

Treating skin and scars after radiation therapy is challenging because radiation often causes skin damage, including dryness, redness, and texture changes. Until the final healing process is complete, skin changes resulting from radiation treatment are treated exclusively with EXOBALM cream, which contains tranexamic acid, panthenol, madecassoside, and niacinamide. These ingredients reduce skin sensitivity, accelerate its renewal, and act as antioxidants. It is crucial to note that this therapy is conducted exclusively in medical institutions and strictly under the supervision of a physician.

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