PSA - Marker for Prostate Cancer Detection

Prostate specific antigen (total and free) is one of the most important markers in urology that is primarily used for early detection and monitoring of prostate cancer therapy. Known as PSA, prostate specific antigen is a protein produced in the prostate that plays an important role in male reproductive health, and its level in the blood can indicate the presence of prostate cancer.

Although urologists primarily use this test for early detection and monitoring of prostate cancer therapy, it is also a tool for detecting other benign prostate diseases, such as benign prostatic hyperplasia (BPH), prostatitis, etc. While total PSA is usually used as an initial test to detect prostate cancer, free PSA can be used to further differentiation between benign and malignant changes.

The use of biomarkers, combined with a digital rectal examination and taking into account all factors (age, family history, patient clinical situation etc.), allows for an accurate diagnosis and provides useful information for disease management for both patients and physicians.